Cardiovascular Pathology Forecasting in Trained Workers Exposed Mercury

DOI

10.2991/itsmssm-16.2016.78How to use a DOI?

Keywords

Forecasting, ceruloplasmin, mercury poisoning, hypertension, coronary heart disease

Abstract

There were examined 77 people trained workers exposed in the workplace of metallic mercury vapors from 4-5 year intervals, who were divided into groups according to the time at the time of examination: I group - 5-9 years, II group - 10-15 years old, III group - 15 years or more. All individuals were studied levels of ceruloplasmin level and gamma glutamyltransferase in the blood serum, atherogenic index, cholesterol levels in low density lipoproteins (LDL). Forecasting was performed using multiple linear regression straight stepwise procedure of adding features. Dynamic examination of trained workers in contact with the mercury, showed an increase of hypertension and coronary heart disease with increasing work experience. The incidence of hypertension and coronary heart disease increased by 1.5-2 times, exceeding the general population prevalence rates in these age groups. Analysis of biochemical parameters at the time of examination allows us to conclude that the atherogenic index increases with increasing exposure mercury load, cholesterol of low density lipoprotein does not go beyond the boundaries of acceptable values, but close to the upper border of the reference (3.8 mmol/l). Considering the significant increase in the predicted concentration of ceruloplasmin in 4-5 years, should expect an intensification of pro-atherogenic process, requiring preventive measures, aimed primarily at enhancing antioxidant protection.

Copyright

© 2016, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Irina Kudaeva
AU  - Elena Katamanova
AU  - Olga Dyakovich
AU  - Viktor Rukavishnikov
PY  - 2016/05
DA  - 2016/05
TI  - Cardiovascular Pathology Forecasting in Trained Workers Exposed Mercury
BT  - Proceedings of the 2016 Conference on Information Technologies in Science, Management, Social Sphere and Medicine
PB  - Atlantis Press
SP  - 390
EP  - 395
SN  - 2352-538X
UR  - https://doi.org/10.2991/itsmssm-16.2016.78
DO  - 10.2991/itsmssm-16.2016.78
ID  - Kudaeva2016/05
ER  -