The Biological Behavior of Osteoblast on the TiO2 nanotube array coating

DOI

10.2991/meep-15.2016.47How to use a DOI?

Keywords

TiO2 nanotube; osteoblast; size-dependent effect; osteopontin protein

Abstract

TiO2 nanotube arrays formed by anodic oxidation on titanium surface can effectively promote osteoblast’ migration, proliferation and other biological behavior, and it has potentials of loading drugs and biological agents. In this study, TiO2 nanotube arrays with different diameters were prepared by anodic oxidation and their effects on the biological behavior of osteoblast were also investigated. It’s found that the osteoblasts exhibit a certain size-dependent effects at the nanoscale. TiO2 nanotube arrays with small diameter can promote cell proliferation, migration and biological activity. The interactions between nanotubes with adhesion proteins integrin are the main factors contributing to this effect.

Copyright

© 2016, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - X.G. Shi
AU  - A. Tian
AU  - H. Yang
AU  - X.X. Xue
PY  - 2016/03
DA  - 2016/03
TI  - The Biological Behavior of Osteoblast on the TiO2 nanotube array coating
BT  - Proceedings of the 2015 International Conference on Materials Chemistry and Environmental Protection (meep-15)
PB  - Atlantis Press
SP  - 178
EP  - 181
SN  - 2352-541X
UR  - https://doi.org/10.2991/meep-15.2016.47
DO  - 10.2991/meep-15.2016.47
ID  - Shi2016/03
ER  -