All of the articles in this proceedings volume have been presented at the TURAKULOV READINGS on 12 November 2025 in Tashkent, Uzbekistan. These articles have been peer reviewed by the members of the Scientific Committee and approved by the Editor-in-Chief, who affirms that this document is a truthful...

This article provides a comprehensive analysis of the endocrinology service in the Republic of Uzbekistan, tracing its historical evolution, current state, and future development prospects. It details significant achievements in infrastructure modernization, the integration of innovative diagnostic and...

Diabetic ketoacidosis (DKA) remains one of the leading causes of hospitalization, mortality, and severe complications, especially in childhood and adolescence. Understanding the interplay between HbA1c levels and DKA resolution time is of paramount importance, as it can provide insights into the underlying...

Fibroblast Growth Factors (FGFs) play a crucial role in renal physiology and pathology, but their optimal diagnostic thresholds across different stages of kidney dysfunction remain unclear. This study aims to determine stage-specific FGF thresholds and assess their diagnostic accuracy in chronic kidney...

Obesity is a significant public health issue in Uzbekistan, increasing the risk of non-communicable diseases. Accurate assessment of body fat and metabolic risks is crucial for early intervention. A cross-sectional study was conducted in 2024 at the Republican Specialized Scientific-Practical Medical...

The study aims to investigate anthropometric parameters, hormonal indicators, and quality of life in patients with obesity, with a focus on somatotropic function. The study included 800 patients with obesity and 20 healthy individuals in the control group. Anthropometric measurements (BMI, waist-to-hip...

Neurogenesis continues until approximately 25 years of age; however, only a limited number of studies have investigated the neurobehavioral consequences of hyperthyroidism in children and adolescents. The effects of hyperthyroidism on cognitive and intellectual development remain insufficiently studied,...

Elevated ACTH levels have been observed in obese patient with hyperinsulinemia, potentially contributing to hypothyroid-like states through impaired T4-to-T3 conversion. We present the case of an 18-year-old female with a long-standing history of obesity (BMI: 47 kg/m2), hyperphagia, and symptoms consistent...

This article explores the impact of inactive pituitary adenoma on the development of hypogonadotropic hypogonadism in women. A clinical study was conducted on 76 female patients aged 18 to 47 years to assess hormonal changes and clinical manifestations. The study found that hypogonadotropic hypogonadism...

Inactive pituitary adenoma (IPA) or “Silent Pituitary Adenomas” refers to tumors that secrete one or more hormones or their transcription factors (TFs), detected by immunohistochemistry (IHC), but the amount of hormones expressed is not has clinical significance and is not expressed by symptom complexes...

The aim of the study is to study the quality of life of patients with thyroid nodules in the Kashkadarya region using the author’s RTQoL (Reproductive and Thyroid Quality of Life) questionnaire. A total of 491 women of reproductive age (prospectively) with thyroid nodules (TN) were examined in the period...

Type 1 diabetes (T1D) among children and adolescents in Uzbekistan shows a steady increase in both incidence and prevalence. This reseach aims to analyze the dynamics of T1D prevalence and incidence among children and adolescents in Uzbekistan from 2017 to 2024 and compare the findings with data from...

The article examines changes in obesity indicators in the Republic of Uzbekistan during the period from 2022 to 2024. Data on obesity incidence across regions were analyzed, with a focus on areas showing the highest growth rates. Obesity in Uzbekistan is becoming an important public health issue, associated...

This research aims to clarify morphological and aesthetic disorders of the dentofacial system, lateral cephalometric radiographs of the head were performed in individuals aged 7 to 23 years, who were divided into two groups: Group 1 – patients with ENT diseases and impaired nasal breathing; Control group...

This study aims to evaluate the current prevalence of iodine deficiency diseases (IDD) among the organized population of the Republic of Karakalpakstan. An epidemiological survey was conducted, involving a random sample of 299 children from schools and kindergartens. A total of 250 urine samples were...

Early and precise identification of primary brain tumors is still a great clinical challenge due to tumor heterogeneity and ambiguous histopathology primary tumours are the most common tumour types in the central nervous system (CNS) with four WHO grades of malignancy (I- IV) associated with tumour growth...

Thyroid cancer remains one of the most common endocrine malignancies, with a steady global increase in incidence. In Uzbekistan, persistent iodine deficiency continues to influence the structure and clinical course of thyroid malignancies. This research aims to evaluate clinical, morphological, hormonal,...

Neuroischemic diabetic foot syndrome (DFS) in patients with chronic kidney disease (CKD) represents one of the most severe and prognostically unfavorable clinical scenarios, where the use of traditional iodinated contrast angiography is often limited by the risk of contrast-induced nephropathy. This...

Disorders of sexual development in boys and adolescents represent an urgent problem in pediatric endocrinology and medical genetics, as they can lead not only to endocrine and reproductive dysfunction but also to persistent infertility in adulthood. One of the possible factors influencing spermatogenesis...

The article is dedicated to the issue of hygienic monitoring of radiofrequency (RF) electromagnetic radiation (EMR) and its impact on biological objects. The authors discuss the relevance of the topic considering the widespread use of mobile communications, Wi-Fi, and other wireless technologies, which...