Volume 2, Issue 2, April 2021
Rotimi E. Aluko
Pages: 49 - 58
Acetylcholinesterase (AChE) is a critical enzyme involved in nerve functions and signal transmission within the brain. However, during aging, excessive AChE activity often leads to rapid and progressive depletion of acetylcholine (ACh), the major neurotransmitter. Shortage of ACh leads to reduced neurotransmission...
2. Behavior of Non-Digestible Polysaccharides in Gastrointestinal Tract: A Mechanistic Review of its Anti-Obesity Effect
Yajun Zhang, Qingtong Xie, Lijun You, Peter Chi-Keung Cheung, Zhengang Zhao
Pages: 59 - 72
Nowadays, obesity in humans is a huge challenge requiring effective, readily available, and low-risk alternative treatments. Intake of edible Non-Digestible Polysaccharides (NDPs) is regarded as a promising strategy to combat obesity. Herein, an overview of the behavior of NDPs in the Gastrointestinal...
3. Combination of Microwave, Ultrasonic, Enzyme Assisted Method for Curcumin Species Extraction from Turmeric (Curcuma Longa L.) and Evaluation of their Antioxidant Activity
Chengke Wang, Hanli Yang, Jiangyu Li
Pages: 73 - 80
The combination of microwave irradiation, ultrasonication treatment, and enzyme-assisted extraction approach was applied to study the extraction efficiency and antioxidative activity of curcumin from turmeric (Curcuma longa L.) using Response Surface Optimization (RSM). The effects of the power and treatment...
Yongpeng Wang, Guy Sedar Singor Njateng, Tianrui Zhao, Meilian Yang, Yifen Wang, Jianxin Cao, Yaping Liu, Guiguang Cheng
Pages: 81 - 91
The buds of Vaccinium dunalianum Wight (VD) are widely used in Yunnan as herbal tea [Que Zui Tea (QT)] and herb. However, the security and toxicity of QT have not been determined yet. The aim of this study is to evaluate the acute and subacute-toxicity of hot water (QTW) and aqueous-ethanol (QTE) extracts...
5. Dendrobine Suppresses Lipopolysaccharide-induced Gut Inflammation in a Co-culture of Intestinal Epithelial Caco-2 Cells and RAW264.7 Macrophages
Huifan Liu, Jiaxi Liang, Gengsheng Xiao, Lukai Ma, Qin Wang
Pages: 92 - 99
We evaluated dendrobine for its potential effect on Inflammatory Bowel Disease (IBD) progression using the intestinal epithelial Caco-2/RAW264.7 macrophage co-culture cell model. The results showed that dendrobine maintained the tight junction (TJ) proteins in co-cultured Caco-2 cells, suggesting its...