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Background: We tested the association between birthweight and arterial stiffness measured by aortic pulse wave velocity (PWV) and cardio-ankle vascular index (CAVI) in a birth cohort of 30 year old Jamaicans. Methods: Participants were from the 1986 Jamaica Birth Cohort. Arterial stiffness was measured...

A non-invasive approach for the estimation of mechanical efficiency through the calculation of the ratio between stroke work and HR-pressure product has been recently proposed by de Simone et al. This index, which expresses the amount of blood pumped in a single beat in 1 second by the heart, may be...

Purpose: Changes in myocardial and arterial wall properties/function are consistently reported in patients with established cardiovascular disease1. However, few studies have reported these changes in early subclinical disease. The aim of the present study was to examine cardiac and vascular changes...

Background: Patients with COPD have increased Cardiovascular (CV) risk and commonly present with altered body composition. Patients with COPD and a low BMI have poorer health outcomes1, while obesity may increase CV risk2. The aim of this analysis was to explore BMI, CV risk, exercise capacity and systemic...

Background: Early stages of chronic obstructive pulmonary disease (COPD) are characterized by loss of the terminal bronchioles and ‘air trapping’ often before overt emphysema manifests (1). COPD patients are also at risk for cardiovascular disease (CVD), therefore, we hypothesized that the degree of...

Rational: Cardiovascular diseases represent the main cause of morbidity and mortality throughout the world (1). Arterial stiffness has shown to be an important predictor of cardiovascular events, and pulse wave velocity (PWV) is a marker of subclinical organ damage which can be measured by different...

Background: Poor sleep quality has been related to poor vascular function and higher risk of cardiovascular disease in the general population. Persons with multiple sclerosis (MS) exhibit a high cardiovascular risk, and report poor sleep quality. To date, the association between sleep quality and vascular...

Hypertension is associated with the risk of cardiovascular disease, metabolic syndrome and central obesity. Hypertension that occurs in adolescence will continue into adulthood. This study aims to identify the incidence of hypertension in adolescents and its relationship with body mass index and abdominal...

High-intensity resistance exercise (RE) acutely increases arterial stiffness and blood pressure (BP), coupled with reduced cerebral blood flow velocity (CBFv) and greater flow pulsatility in the cerebral circulation, which may be detrimental to cerebral microvasculature. Because females have different...

Inflammation is associated with an increased risk of cardiovascular events and reduced endothelial function. Higher cardiorespiratory fitness is associated with lower risk of cardiovascular events and improved vascular function. Whether fitness plays a role during acute inflammation is unknown. Purpose:...

Background: Dementia has been recently viewed as a predominantly vascular disorder. Indeed, reduced brain NO availability causes increased ß-amyloid deposition by several mechanisms, including hypoperfusion. Purpose: To investigate the relationship between cerebral blood flow in the hippocampal and...

Hypertension is a condition in which the blood vessels increase in systolic blood pressure 140 mmHg and / or diastolic 90 mmHg. Hypertension is known as the silent killer, because it has no obvious signs or symptoms. This thesis aims to describe the general characteristics of sex, nutritional intake...

Deficiency of vitamin D in the world is high. Vitamin D deficiency has numerous negative effects. The purpose of this study was to determine the proportion of vitamin D deficiency in male adolescents in Yogyakarta Indonesia. This research is a cross-sectional study. The height, weight, physical activity,...

The study aims to investigate anthropometric parameters, hormonal indicators, and quality of life in patients with obesity, with a focus on somatotropic function. The study included 800 patients with obesity and 20 healthy individuals in the control group. Anthropometric measurements (BMI, waist-to-hip...

Diabetes, as one of the most severe chronic diseases globally, has seen an increase in prevalence in recent years rather than a decrease. Early screening for diabetes relies on traditional biochemical indicators, resulting in a high rate of missed diagnoses and insufficient resources at the grassroots...

Background: Age and blood pressure (BP) are known to be the main determinants of large artery stiffness. However other factors may lead to an inappropriately high pulse wave velocity (PWV). We investigated the determinants of inappropriately high PWV in hypertensive patients and their possible role in...

Background: Several works analyze arterial parameters’ (stiffness levels, wall thickness, etc.) association with variations of body mass index (BMI) in pediatric populations. However, none integrate different arterial parameters as comparable continuous (standardized) variables, in order to assess their...

Background: Arterial stiffness (AS), as pulse wave velocity (PWV), is a powerful independent predictor of cardiovascular events and commonly complicates type 2 diabetes (T2D). This trial aims to test if AS, measured by the VaSera machine as cardio-ankle vascular index (CAVI) and by Arteriograph measuring...

Hypertension, commonly known as high blood pressure, is a condition characterized by a persistent increase in pressure within the arterial system. Professional drivers face a higher risk of developing hypertension due to factors such as genetics, lack of physical activity, obesity, excessive salt intake,...

Central obesity is an important cause of cardiovascular disease. It’s well-known that aortic pulse wave velocity (aoPWV) is a strong predictor of cardiovascular events. However the potential correlation between fat accumulation and increased arterial stiffness is poorly investigated. The aim of this...

Body mass index (BMI) is an approximate measure of your total body fat. Being underweight or overweight can cause health problems, especially if you are also inactive. These problems include heart disease and cardiovascular problems, diabetes, digestive problems, breathing problems and other problems....

We aimed at evaluating the anthropometric and hemodynamic factors associated with central pulse pressure (cPP), peripheral pulse pressure (pPP) and central-to-peripheral PP amplification (PPamp) in healthy adolescents. We studied 459 subjects (boys 57%, 16.8 ± 1.5 y) attending the Liceo Donatelli High...

Background: Central blood pressure (CBP) is a better predictor of cardiovascular burden than peripheral blood pressure (BP). While studies have suggested a reduction in peripheral BP with statins, it remains uncertain to what extent statins reduce CBP and whether this reduction is mediated through a...

Diseases that are mostly suffered by the elderly include hypertension, heart disease, and diabetes mellitus. One of the non-communicable diseases that cause mortality and morbidity in Indonesia is hypertension, the management of which is commonly practiced at various levels of health facilities. The...

Introduction: Peripheral neuropathy is a nerve disorder in the foot caused by chronic diabetes, and damage the sensory nerves. Initially, patients will complain of numbness, and gradually have an impact on the inability to feel the stimulation of pain that triggers gangrene wounds and even infections....

The contribution of arterial functional and structural changes to left ventricular (LV) diastolic dysfunction has been the area of latest research. There are some studies on the relationship of arterial stiffness (a.s.) and left atrial (LA) remodeling as a marker of diastolic burden. Little is known...

Diabetes is the fourth leading cause of death globally, causing 1.6 million deaths annually. This study aimed to analyze the risk factors for type II diabetes mellitus at the Siulak Gedang Community Health Center, Siulak District, Kerinci Regency. Using a cross-sectional design with accidental sampling,...

Sleep is a major modulator of cardiovascular function. Since it’s more difficult to maintain adequate sleep duration among night watchmen during their working schedule, so in this study, we hypothesized that, the short sleep duration (<3 h) for 7 days in their night shift schedule, may possibly influence...

Obesity is one of the health problems in Indonesia. According to Indonesia’s Research Data Institute in 2013, the prevalence of obesity in Indonesia is greater in women and the age group of 50–54 years old. Obesity is one of the risk factors of various diseases, one of them is lumbar lordosis because...

Aim: Type 2 diabetes (DM2) causes microvascular dysfunction (MVD). In addition, MVD can contribute to insulin resistance, predisposing to DM2. This hypothesis predicts that MVD should be present in impaired glucose metabolism (IGM; prediabetes). However, population-based studies of MVD and glucose metabolism...

Decreases in the mean gestational age of babies born at term have been reported over the past decade in several developed countries, linked to increases in the rates of planned births by labour induction and/or pre-labour caesarean sections. In contrast to the effects of pre-term birth, the extent to...

Obesity is a significant public health issue in Uzbekistan, increasing the risk of non-communicable diseases. Accurate assessment of body fat and metabolic risks is crucial for early intervention. A cross-sectional study was conducted in 2024 at the Republican Specialized Scientific-Practical Medical...

The pathophysiology of infertility in endometriosis is still controversial and widely investigated. Several mechanisms are put forward. Whether In Vitro Fertilization-Embryo Transfer (IVF-ET) program in endometriosis is a solution to improve the fertility still needs further studied. Objective : To compare...

Introduction: COPD is associated with increased cardiovascular risk, independent of established risk factors. Arterial stiffness is a surrogate of cardiovascular risk and we sought to determine its relationship with COPD severity and prognosis in the ERICA (Evaluation of role of inflammation in airways...

Childhood determinants of aortic pulse wave velocity [PWV] are poorly understood. We tested how factors measured twice previously in childhood in the MRC ‘DASH’ study, particularly body mass (BMI) components and BP, affected PWV in young adults. Methods: Of 6643 London children, aged 11–13 y, from 51...

African Americans are more susceptible to develop insulin resistance, obesity, Type 2 diabetes, and coronary heart disease (CHD), and systemic inflammation is central to the pathophysiology of these chronic diseases. African Americans are also more likely to contract H. pylori (cagA) infections during...

Background/aim: Preeclampsia is one of the causes of increased maternal mortality. The rate in East Java Province reached 91 per 100,000 live births. The highest cause of maternal death in 2016 was preeclampsia/eclampsia, which was 30.90% or 165 people. This study aims to determine the relationship of...

Background: Vascular stiffness predicts cardiovascular disease (CVD). Pulse wave velocity (PWV), reflecting vascular stiffness, though determined largely by mean arterial pressure; is also sensitive to insulin and glucose. Capacitance in small (C2) and large vessels (C1), reflecting vascular responsiveness...

Introduction: Bariatric surgery in extremely obese patients has influence on metabolic variables and body weight however data about influence on flow-mediated dilatation (FMD) of brachial artery are inconsistent. The aim of the study was to assess the effect of bariatric surgery on endothelial function...

Objective: Morning surge of peripheral blood pressure (BP) is considered to be an independent risk factor for cardiovascular diseases. However, morning central blood pressure surge (MCBPS) has not been analyzed so far. Therefore, the aim of study was to evaluate the variables independently associated...

Anthropometric profile and motor skill are dominant factors influencing the performance of volleyball players. The aim of the research was to know the anthropometric profile and motor skill of the club elite players. This study was a cross sectional study involving 45 men elite volleyball players of...

Objective: The changing living patterns in China are accompanied by an increase in prevalence of cardiovascular disease for which obesity is a significant factor. This study investigated the association between obesity phenotypes and risk of cardiovascular disease in a Chinese cohort. Methods: A sample...

Introduction: In men with hypertension, obstructive sleep apnea (OSA) is associated with increased arterial stiffness. However, it is not clear if the impact of OSA on patients with hypertension is similar in women. Methods: We recruited consecutive patients with established diagnosis of hypertension...

Objective: To investigate the relationship between arterial function and cardiac, especially left ventricular (LV) diastolic, function, in people at risk of or with type 2 diabetes (T2DM). Design and method: 64 patients (48% non-European) participated in the study. Cardiac indices were obtained by 2-dimensional...

Type 2 Diabetes Mellitus (T2DM) is a metabolic syndrome disease that could lead to coronary heart disease (CHD). The pathogenesis related to dyslipidemia. The LDL/HDL ratio could be classified as a risk indicator. Many factors can affect this ratio, including body mass index (BMI) and blood pressure...

Objective: to investigate features of arterial remodeling and distensibility in marathon runners by a multi-site, non-invasive approach. Methods: 46 marathon runners (M) and 15 age-sex- and BMI matched sedentary (S) individuals were recruited (men 70 vs 67%, p=0.83; age 44±7 vs 43±6 years, p=0.62; BMI...

Objective: To assess if 24h urinary cortisol metabolite (UCM) profiles are related to structural cardiac and arterial parameters in those with or at risk of Type 2 diabetes mellitus (T2DM). Design and method: 32 participants, 25-77 years, eGFR> 45 mL/min and no serious illness. Urine was collected...

The aim of this study was to evaluate vascular and echocardiographic markers of hypertension (HT) in subjects with newly diagnosed HT before treatment started. We studied 32 patients with newly diagnosed HT without pharmacological therapy (HT group) and 31 healthy ones (control group). ABPM were performed...

Background: Maximum aerobic capacity (VO2max) is associated with lower cardiovascular and total mortality. Step tests can be used to provide an estimate of (VO2max) in epidemiological or home-based studies. We compared different methods of estimation of VO2max and heart rate recovery and evaluated the...

This study aimed to determine the nutritional status and physical fitness of students Junior High School No. 15 Padang. This study was descriptive that involved 66 students. To determine the nutritional status of students using the formula BMI = weight / TB2 and physical fitness using physical fitness...