Artery Research

Latest Articles

Research Article

Pulse Wave Velocity Comparing Estimated and Direct Measures of Path Length in Older Women

Ludovica Bognoni, Marina Cecelja, Tarique Hussain, Gerald Greil, Tim Spector, Philip Chowienczyk, J. Kennedy Cruickshank
In Press, Corrected Proof, Available Online: 27 August 2020
Background: Carotid-femoral Pulse Wave Velocity (cfPWV) is the gold-standard measure of arterial stiffness. Accuracy of non-invasive cfPWV as meters per second is impeded by surface estimates of aortic length. Our aim was to compare cfPWV measured using distance estimated from surface measurements with...
Letter to Editor

“Letters from” during the 2020 COVID-19 Pandemic

John Cockcroft
In Press, Corrected Proof, Available Online: 20 August 2020
Research Article

Novel Aspects of Differences in Arterial Stiffness Parameters during Short Abstinent Period in Smokers vs. Non-smokers

Zsófia Mrekváné Burián, Annamária Pakai, Attila Cziráki, Zsófia Verzár
In Press, Corrected Proof, Available Online: 7 August 2020
Although the effects of smoking on hemodynamics and arterial stiffness has already been evaluated from many aspects, self-controlled and 24-h data have remained a missing area. Ten healthy light smokers were examined in a cross-sectional observational study for 48 h [smoking was prohibited during the...
Research Article

Effects of Weight Loss on Vascular Function in Obese Individuals with Poor Cardiovascular Health: Design and Research Protocol of an Interventional Clinical Trial

Michelle Rabello Cunha, Samanta Souza Mattos, Marcia Regina Simas Torres Klein, Wille Oigman, Mario Fritsch Neves
Volume 26, Issue 3, September 2020, Pages 154-160
Introduction: Excessive adipose tissue is associated with adverse metabolic effects and is an important risk factor for chronic diseases. According to the American Heart Association, most cardiovascular events can be prevented by adhering to healthy practices, reflecting cardiovascular health as poor,...
Research Article

Association between Mental Health and Arterial Stiffness in Middle-aged and Older Adults

Nobuhiko Akazawa, Koichiro Tanahashi, Keisei Kosaki, Ai Hamasaki, Seiji Maeda
In Press, Corrected Proof, Available Online: 27 July 2020
Background: Mental stress is a risk factor for cardiovascular disease. However, little is known about the impact of mental stress on arterial function in middle-aged and older adults. Objective: This study is aimed to investigate the association between mental stress and arterial function in this population. Methods:...
Review Article

The Human Systemic and Cerebral Circulations: Contrasts in Structure and Function

Michael O’Rourke, Jonathan Stone, Audrey Adji, Mi Ok Kim, Yan Li, Ji Guang Wang, Alberto Avolio, Per Kristian Eide, Marek Czosnyka
In Press, Corrected Proof, Available Online: 19 July 2020
Apart from peculiarities of the cerebral circulation, required to perfuse the brain with the subject erect, the principles established for function of the human systemic circulation (pulsatile flow at input and steady flow at output in capillaries) are identical to those established for other mammals....
Research Article

Protocol of the SPARTE Study: A Strategy for Preventing Cardiovascular and Renal Events based on ARTErial Stiffness

Stephane Laurent, Gilles Chatellier, Michel Azizi, David Calvet, Gabriel Choukroun, Nicolas Danchin, Pascal Delsart, Philippe Gosse, Gerard London, Jean-Jacques Mourad, Bruno Pannier, Helena Pereira, Dominique Stephan, Pierre Boutouyrie, On Behalf of SPARTE Investigators
In Press, Corrected Proof, Available Online: 17 July 2020
Whether arterial stiffness is a surrogate end-point for cardiovascular and renal disease has never been directly demonstrated by a controlled clinical trial. Our main hypothesis is a better prevention of outcomes in high risk hypertensives with PWV normalization driven strategy than with usual blood...
Review Article

Accurate Measurement of Blood Pressure

Dean S. Picone
Volume 26, Issue 3, September 2020, Pages 130-136
Accurate Blood Pressure (BP) measurement is vital for appropriate diagnosis and management of cardiovascular risk. However, questions remain on the accuracy of cuff BP compared with invasive (intra-arterial) BP. Moreover, the critical physiological factors that are associated with inaccuracy of cuff...
Research Article

Measurement of Instantaneous Wave-free Ratio through a Diagnostic Catheter: Comparison of the Results between 4Fr and 5Fr

Shinichiro Masuda, Ryota Uemura, Yoshiyuki Saiki, Tatsuo Haraki, Takeshi Lee
Volume 26, Issue 3, September 2020, Pages 143-147
Background: Clinical evidence of coronary pressure assessment through a diagnostic catheter is limited. The aim of this study was to assess the difference, safety, and rate of successful measurement of Instantaneous Wave-free Ratio (iFR) through 4Fr and 5Fr diagnostic catheters. Methods: This single-centre...
Research Article

Acute Effects of Self-myofascial Release using a Foam Roller on Arterial Stiffness in Healthy Young Adults

Sascha Ketelhut, Martin Möhle, Kuno Hottenrott
In Press, Corrected Proof, Available Online: 18 June 2020
This study aimed to investigate whether a single bout of Self-myofascial Release (SMR) has a beneficial effect on peripheral and central Blood Pressure (BP) and different parameters of arterial stiffness. Twenty nine healthy male recreational athletes (26.1 ± 2.9 years, BMI 23.4 ± 1.5 kg/m2) completed...
Letter to Editor

Response to the letter to editor “Arterial Stiffness Measurement in Metabolic Syndrome Patients”

Angela Cozma, Adela Sitar-Taut, Olga Hilda Orasan, Pierre Boutouyrie
In Press, Corrected Proof, Available Online: 17 June 2020
Letter to Editor

Arterial Stiffness Measurement in Metabolic Syndrome Patients

Javad Alizargar
In Press, Corrected Proof, Available Online: 17 June 2020
Research Article

Implications of Changing the Asymptotic Diastolic Pressure in the Reservoir-wave Model on Wave Intensity Parameters: A Parametric Study

N. Pomella, E.R. Rietzschel, P. Segers, Ashraf W. Khir
In Press, Corrected Proof, Available Online: 15 June 2020
Hybrid reservoir-wave models assume that the measured arterial pressure can be separated into two additive components, reservoir/windkessel and excess/wave pressure waveforms. Therefore, the effect of the reservoir volume should be excluded to properly quantify the effects of forward/backward-travelling...
Case Study

Supine Hypertension and Extreme Reverse Dipping Phenomenon Decades after Kidney Transplantation: A Case Report

Dóra Batta, Beáta Kőrösi, János Nemcsik
Volume 26, Issue 3, September 2020, Pages 183-186
Background: Supine hypertension, a consequence of autonomic neuropathy, is a rarely recognized pathological condition. Reported diseases in the background are pure autonomic failure, multiple system atrophy, Parkinson’s disease, diabetes and different autoimmune disorders. Methods: In our case report...
Research Article

A Computational Study of the Effect of Stent Design on Local Hemodynamic Factors at the Carotid Artery Bifurcation

Nasrul Hadi Johari, Mohamad Hamady, Xiao Yun Xu
Volume 26, Issue 3, September 2020, Pages 161-169
Background: Previous clinical studies have shown that the incidence of restenosis after carotid and coronary stenting varies with stent design and deployment configuration. This study aims to determine how stent design may affect in-stent hemodynamics in stented carotid arteries by means of Computational...
Short Communication

Mild Acute Inflammation does not Impair Maintenance of Blood Pressure during a Hypotensive Stimulus

Elizabeth C. Schroeder, Thessa I. M. Hilgenkamp, Wesley K. Lefferts, Bo Fernhall
Volume 26, Issue 3, September 2020, Pages 180-182
Research Article

Role of Adipose Tissue and Skeletal Muscle in Atherosclerosis and in Central Hemodynamics

Joana Ferreira, Pedro Cunha, Armando Mansilha, Cristina Cunha, Cristina Silva, Isabel Vila, Alexandre Carneiro, Amílcar Mesquita, Jorge Cotter
Volume 26, Issue 2, June 2020, Pages 76-83
Background: Carotid Arterial Disease (CAD) and peripheral arterial disease (PAD) are atherosclerotic diseases. Adipose tissue (AT) and skeletal muscle (SM) are endocrine organs producing polypeptides with vascular effects. The main objective of this study is to characterize the AT and SM in PAD and CAD....
Research Article

Myocardial Bridge Anatomical Characteristics Relationship with ECG Changes and Markers

Hussein Nafakhi, Abdulameer A. Al-Mosawi, Samet Kasim
Volume 26, Issue 2, June 2020, Pages 84-88
Background: The clinical significance of coronary Myocardial Bridge (MB) anatomical characteristics is controversial in the literature. It is not clear whether MB has a benign or malignant clinical outcome. Objectives: To investigate the possible relationship between MB characteristics (depth, length...
Research Article

Association between Rutherford Classification and CHA2DS2-VASc, CHADS2 and ASCVD Scores in Peripheral Artery Disease Patients

Bilge Duran Karaduman, Hüseyin Ayhan, Telat Keleş, Engin Bozkurt
Volume 26, Issue 2, June 2020, Pages 111-116
Background and Aim: The classification system is important in assessing the severity of Peripheral Artery Disease (PAD) and making the treatment decision. However, classification systems may not be sufficient and scoring systems developed to predict cardiovascular and cerebrovascular events can also...
Review Article

The European COST Action VascAgeNet Fostering Innovation – When Industry Comes to Science

Christopher C. Mayer, Rachel E. Climie, Bernhard Hametner, Rosa-Maria Bruno
Volume 26, Issue 3, September 2020, Pages 125-129
VascAgeNet is a new European network which will join forces in order to refine, harmonize and promote the vascular ageing concept. It aims to bring innovations in cardiovascular research from bench to bedside and to establish assessment of vascular ageing in clinical practice. The interdisciplinary,...
Research Article

Rationale and Design of a Randomized Controlled Trial to Evaluate the Effects of Probiotics during Energy Restriction on Blood Pressure, Body Composition, Metabolic Profile and Vascular Function in Obese Hypertensive Individuals

Marcella Rodrigues Guedes, Karine Scanci da Silva Pontes, Débora Cristina Torres Valença, Wille Oigman, Mario Fritsch Neves, Márcia Regina Simas Torres Klein
Volume 26, Issue 2, June 2020, Pages 102-110
Introduction: Hypertension often clusters with other cardiovascular risk factors such as obesity, dyslipidemia and glucose intolerance. Weight loss can decrease Blood Pressure (BP) and improve cardiometabolic abnormalities. There is evidence that hypertension and obesity are associated with alterations...
Case Study

The Curious Case of a Missing Coeliac Trunk: A Case Report and Review of the Literature

Erin Cihat Saricilar, Ashley Peter Heyworth, Animesh Singla
Volume 26, Issue 2, June 2020, Pages 121-124
Introduction: The anatomy of the coelic trunk is highly variable. An understanding of the variations is important in general and vascular surgery due to the implications of disruption and consequent visceral ischaemia. Case Description: A case is described of a 69-year-old woman presenting with undifferentiable...
Short Communication

Reflections Revisited, Reinterpretation Required✩

Berend E. Westerhof, Lex M. van Loon, Nico Westerhof
Volume 26, Issue 2, June 2020, Pages 117-120
Research Article

Study Protocol – Insight 46 Cardiovascular: A Sub-study of the MRC National Survey of Health and Development

Sarah Ann Mason, Lamia Al Saikhan, Siana Jones, Gemma Bale, Sarah-Naomi James, Heidi Murray-Smith, Alicja Rapala, Suzanne Williams, Brian Wong, Marcus Richards, Nick C. Fox, Rebecca Hardy, Jonathan M. Schott, Nish Chaturvedi, Alun D. Hughes
Volume 26, Issue 3, September 2020, Pages 170-179
The commonest causes of dementia are Alzheimer’s disease and vascular cognitive impairment. Although these conditions have been viewed as distinct entities, there is increasing evidence that neurodegenerative and vascular pathologies interact or overlap to cause cognitive decline, and that at least in...
Review Article

Monoclonal Antibodies in Oncology and their Effect on Arterial Stiffness – A Systematic Review

Eirini Solomou, Konstantinos Aznaouridis, Dimitrios Terentes-Printzios, Maria Drakopoulou, Konstantinos Toutouzas, Dimitris Tousoulis, Charalambos Vlachopoulos
Volume 26, Issue 3, September 2020, Pages 137-142
Introduction: Malignancies are the second leading cause of death worldwide. Treatment Monoclonal Antibody (MAbs)-based treatment of cancer has been established as one of the most successful therapeutic strategies in the last 20 years; however, there is a growing concern about the effects of these agents...