Saana Karelius, Jussi Vahtera, Olli J. Heinonen, Teemu J. Niiranen, Sari Stenholm
Volume 27, Issue 3, September 2021, Pages 129-134
Objective: Besides traditional risk factors, other factors such as life stressors are linked with incident cardiovascular disease. However, the underlying mechanisms for this association remain mostly unknown. We studied the relation of life stressors (job strain, sleep loss due to worry, illness or...
Hui Li, Dan Du, Juan Chen, Xiang Wang, Yuanliang Xie
Volume 27, Issue 3, September 2021, Pages 121-128
Objective: To explore the characteristics of pre-existing Cerebral Small Vessel Disease (CSVD) in young patients with Acute Ischemic Stroke (AIS) caused by large artery atherosclerosis or small artery occlusion.
Methods: A total of 400 patients with suspected stroke or transient ischemic attack who...
Alun D. Hughes, Nish Chaturvedi
Volume 27, Issue 1, March 2021, Pages 51-51
Johannes Sperling, Shantanu Sharma, Peter M. Nilsson
Volume 27, Issue 3, September 2021, Pages 112-120
Objective: Our aim was to examine the impact of mismatch patterns reflecting pre- and post-natal growth conditions on markers of arterial stiffness and central hemodynamics in young adults.
Methods: In all, 1056 participants from Malmö Offspring Study, 484 men and 572 women (age-range 18–44 years),...
Lingxiong Chen, Xuming Zhang, Fuyan Jiang, Zhida Yin, Jinqiu Xue, Chengmei Ruan, Lijiao Xie
Volume 27, Issue 2, June 2021, Pages 101-106
Background: Arteriosclerosis Obliterans (ASO) is an important cause for lower limb amputation. We aimed to compare the effects of interventional and conservative therapies on lower extremity ASO, and to analyze the risk factors for prognosis.
Methods: Ninety-eight eligible patients were randomly divided...
Darla L. Tharp, Douglas K. Bowles
Volume 27, Issue 2, June 2021, Pages 93-100
Low, oscillatory flow/shear patterns are associated with atherosclerotic lesion development. Increased expression of KCa3.1 has been found in Vascular Smooth Muscle (VSM), macrophages and T-cells in lesions from humans and mice. Increased expression of KCa3.1, is also required for VSM cell proliferation...
Marina Fukuie, Takashi Tarumi, Takayuki Yamabe, Jun Sugawara
Volume 27, Issue 3, September 2021, Pages 107-111
Frequent assessment of vascular health (e.g., arterial stiffness) may predict the incidence of cardiovascular disease. The Second Derivative of the finger Photoplethysmogram Aging Index (SDPTGAI) may be used as an index of vascular aging and a screening tool for arteriosclerotic disease. To test its...
Guoxiang Fu, Yuan Zhong, Fengfeng Pan, Chanchan Xu
Volume 27, Issue 2, June 2021, Pages 82-86
Background: Brachial-Ankle Pulse Wave Velocity (baPWV) and Ankle-Brachial Index (ABI) are widely used in clinic for evaluating arterial stiffness and atherosclerosis separately. This study aimed to compare the sensitivity of baPWV and ABI for cardiovascular risk assessment in elderly Chinese.
Masaki Yoshioka, Kaname Tagawa, Yuriko Tochigi, Tomohito Sato, Jiyeon Park, Reiko Momma, Youngju Choi, Jun Sugawara, Seiji Maeda
Volume 27, Issue 2, June 2021, Pages 87-92
Background: Exercise training-induced adaptation of central Blood Pressure (BP) depends on exercise mode. Kendo, a traditional Japanese martial art, is a unique exercise mode because its training encompasses anaerobic and resistance training components. However, the effects of habitual kendo training...
Hsin-Fu Lin, Soun-Cheng Wang, Hao-Min Cheng, Jun Sugawara
Volume 27, Issue 2, June 2021, Pages 75-81
Homebased exercise is often advocated to improve physical fitness in the aging population, especially when outdoor activity is not available. Yet we often have a limited understanding of its training effects for clinical uses.
Aim: To investigate a short-term exercise training of standing core exercise...
Nadège Côté, Emy Philibert, Mathilde Paré, Rémi Goupil, Catherine Fortier, Martin G. Schultz, James E. Sharman, Mohsen Agharazii
Volume 26, Issue Supplement 1, December 2020, Pages S84-S84
Purpose/Background/Objective: According to reservoir-wave approach (RWA) arterial pressure is the sum of a reservoir pressure (RP) accounting for dynamic storage and release of blood from arteries, and an excess pressure (XSP) analogous to flow. RP is the minimal left ventricular work required to generate...
Kingsley Duru, Cara Hildreth, Alberto P. Avolio, Jacqueline K. Phillips, Mark Butlin
Volume 26, Issue Supplement 1, December 2020, Pages S85-S85
Purpose: Studies support beneficial effects of isoflavones, but antidiabetic effects of these agents remains unconfirmed [1,2]. This pilot study investigates isoflavones and Inonotus obliquus (chaga) extract effects on diabetes.
Methods: Diabetes was induced (streptozotocin 65 mg/kg, nicotinamide 110...
MPH Lisa Baumgartner, Heidi Weberruß, Katharina Appel, Tobias Engl, Renate Oberhoffer-Fritz, Thorsten Schulz
Volume 26, Issue Supplement 1, December 2020, Pages S83-S83
Purpose: The adaptation process of the cardiovascular system to exercise and muscular strength in young athletes is unclear. Therefore, we investigated the influence of changes in muscular strength and weekly training load within one year on arterial stiffness in young male soccer players.
Joana Ferreira, Alexandre Carneiro, Pedro Cunha, Armando Mansilha, Isabel Vila, Cristina Cunha, Cristina Silva, Adhemar Longatto-Filho, Maria Correia-Neves, Gustavo Soutinho, Luís Meira-Machado, Amilcar Mesquita, Jorge Cotter
Volume 26, Issue Supplement 1, December 2020, Pages S86-S87
Purpose/Background: Sarcopenia (decrease of muscle mass and function) has been linked with atherosclerosis . The EWGSOP2 updated consensus, uses low muscle strength as the primary indicator of sarcopenia . It is acknowledged that strength is better than mass for predicting adverse outcomes ....
Nikolaos Fountoulakis, Salma Ayis, Anastasios Mangelis, Angeliki Panagiotou, Maria Flaquer, Stanimir Stoilov, Giuseppe Maltese, GianCarlo Viberti, Stephen Thomas, Luigi Gnudi, Janaka Karalliedde
Volume 26, Issue Supplement 1, December 2020, Pages S88-S88
Background and Aims: Active vitamin D [1,25(OH)2D3] deficiency is a potential modifiable risk factor for cardiovascular (CVD) and renal disease in patients with type 2 diabetes (T2DM) and stage 3/4 chronic kidney disease (CKD). Exact mechanisms are unclear. Arterial stiffness is an independent predictor...
Florian Stefanov, Dave Veerasingam, Sarah Sayed, Patrick Delassus, Jonathan Bouchier-Hayes, Liam Morris
Volume 26, Issue Supplement 1, December 2020, Pages S92-S92
Background and Objectives: The cushioning effect of large, healthy arteries reduces pulsatile afterload to the heart, reduces pulsatility in the microvasculature of target organs, and promotes coronary/cerebral perfusion . With age, large arteries become stiffer, which increases both pulse wave velocity...
Eleni Gavriilaki, Panagiota Anyfanti, Stella Douma, Eugenia Gkaliagkousi
Volume 26, Issue Supplement 1, December 2020, Pages S89-S89
Purpose/Background/Objectives: Cardiovascular risk is increased in patients with autoimmune rheumatic disorders . Endothelial and platelet MVs (EMVs, PMVs) are small vesicles (0.1–1 μm) released from plasma membrane and represent novel markers of endothelial dysfunction and thrombosis. Their levels...
Emy Philibert, Hasan Obeid, Mathilde Paré, Nadège Côté, Catherine Fortier, Rémi Goupil, Mohsen Agharazii
Volume 26, Issue Supplement 1, December 2020, Pages S90-S90
Purpose/Background/Objective: We have previously shown that restoration of kidney function through kidney transplantation (KTx) is associated with improved aortic stiffness. In this study, we aim to examine whether this change in aortic stiffness translates into improvement of radial artery systolic-diastolic...
Constantinos Anagnostopoulos, Stavroula Giannouli, Nikolaos Ioakimidis, Paulos Kafouris, Iosif Koutagiar, Anastasia Sioni, Eirini Solomou, Dimitrios Terentes-Printzios, Dimitrios Tousoulis, Charalampos Vlachopoulos
Volume 26, Issue Supplement 1, December 2020, Pages S91-S91
Introduction: Anti-cancer treatment can lead to increased cardiovascular morbidity among lymphoma survivors . This may be the result of direct effect of treatment on heart function, or indirect acceleration of atherosclerosis. 18F-fluorodeoxyglucose (FDG) uptake is a sensitive and robust marker for...
Sara Rodrigues, Renata G S Verardino, Marcel J A Costa, Ana Luíse Duenhas-Berger, Valéria Costa-Hong, Luiz A Bortolotto
Volume 26, Issue Supplement 1, December 2020, Pages S78-S78
Purpose: To compare augmentation index (AIx) between one Moderate-intensity continuous physical exercise (MICPE) and one High-intensity interval physical exercise (HIIPE) session in normal/high normal blood pressure (BP) (120–140 for systolic and 80–90 mmHg for diastolic). Additionally, to compare two...
Andrea Guala, Daniel Gil Sala, Aroa Ruiz-Muñoz, Marvin Garcia-Reyes, Lydia Dux-Santoy, Gisela Teixido-Tura, Cristina Tello, Filipa Valente, Angela Lopez-Sainz, Laura Galian, Laura Gutierrez, Kevin Johnson, Oliver Wieben, Ignacio Ferreira, Arturo Evangelista, Sergi Bellmunt-Montoya, Jose Rodriguez-Palomares
Volume 26, Issue Supplement 1, December 2020, Pages S74-S75
Background: Thoracic endovascular aortic repair (TEVAR) is becoming the preferred treatment option to repair the proximal descending aorta after rupture following blunt traumatic injury. However, hemodynamic and mechanic implications of this intervention are poorly understood. Exploiting the possibilities...
Maryam Bukhamseen, Nada Al-Saileek, Ahmed Al-Saileek, Mohammad Ghormalla Ghamdi, Tahlil Wasame, Ahmed Omran, Azra Mahmud
Volume 26, Issue Supplement 1, December 2020, Pages S76-S76
Background: In the early stages of atrial remodeling, increased aortic stiffness might indicate atrial fibrosis.
Objective: This study aimed to investigate the association between left atrial (LA) mechanical function, assessed by two-dimensional speckle tracking echocardiography and aortic stiffness...
Federica Poli, Rosa Maria Bruno, Francesco Faita, Hakim Khettab, Michel Azizi, Saverio Vitali, Mirco Cosottini, Davide Caramella, Lorenzo Ghiadoni, Stefano Taddei, Pierre Boutouyrie, Alexandre Persu, Xavier Jeunemaitre, Aurélien Lorthioir
Volume 26, Issue Supplement 1, December 2020, Pages S73-S73
Rationale and Aim: This study is aimed at identifying possible patterns of vascular wall disarray and remodeling in radial arteries of patients with fibromuscular dysplasia (FMD), by means of ultrahigh frequency ultrasound (UHFUS).
Methods: UHFUS scans of the radial arteries and of 30 FMD patients and...
Lynn Roth, Wim Martinet, Guido R.Y. De Meyer
Volume 26, Issue Supplement 1, December 2020, Pages S79-S80
Background: Acetylsalicylic acid (ASA) is used in secondary prevention of cardiovascular disease (CVD) because of its antithrombotic effects. We investigated whether ASA has additional therapeutic value by preventing the progression of inflammation and cardiovascular remodelling in mice with stable atherosclerosis...
Bart Spronck, Marcos Latorre, Sameet Mehta, Alexander W. Caulk, Abhay B. Ramachandra, Sae-Il Murtada, Alexia Rojas, Chang-Sun He, Bo Jiang, Mo Wang, Matthew R. Bersi, George Tellides, Jay D. Humphrey
Volume 26, Issue Supplement 1, December 2020, Pages S81-S82
Background: Many genetic mutations affect aortic structure and function in mice, but little is known about the influence of background strain. We compared the biomechanical, structural, and gene expression responses of C57BL/6J and 129SvEv aortas to angiotensin II (AngII)-induced hypertension.