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Background: Limited data exists on arterial stiffness in sub-Sahara Africa where diabetes and cardiovascular diseases are increasing rapidly. We aimed to compare the indices of arterial stiffness among type 2 diabetes (T2DM) and non-diabetes subjects (NDM), without hypertension, in Ghana. Method: Thirty...

Few studies have examined whether central arterial wavTable:eform measures vary with ethnicity. We aimed to provide a more comprehensive examination of ethnic differences in several cardiovascular risk factors, which may reveal new ethnic variations. A cross-sectional (baseline) analysis of 5110 adults...

Objectives: In developing countries, urbanization leads to changes in behavioural lifestyle and malnutrition which may lead to higher rates of cardiovascular disease .1,2 We aimed to assess the association between low body mass index and markers of cardiovascular function like pulse wave velocity in...

Background: Carotid-femoral pulse wave velocity (cfPWV) is an independent predictor of cardiovascular events and its measurement is recommended by current hypertension guidelines. Few data are available on the progression of PWV over time. The aim of the present study was to assess the progression of...

Based on the results of the RISKESDAS 2018, the prevalence of hypertension in people aged > 18 years has increased from 25.8% (2013) to 34.1% (2018). Several factors, especially modifiable factors, need to be further identified to prevent an increase in blood pressure in young adults. The objective...

Objectives: In resource-poor settings, aPWV’s prognostic power, independent of blood pressure (BP), has potential as an intervention target against ‘hypertension’ and diabetes (T2DM). We compared simple determinants of aPWV in 3 African-origin settings and British Europeans. Methods: Using methods standardised...

Objectives: Carotid-femoral pulse wave velocity (cfPWV) is a validated non-invasive measure of aortic stiffness. Risk factors for cfPWV are well described in adulthood, and furthermore cfPWV is associated with incident cardiovascular disease in adults (1). However, risk factors for arterial stiffness...

Epidemiological studies show that the prevalence of diabetes mellitus and impaired glucose tolerance (GTG) increase in line with the age. The increase in the prevalence of non-communicable diseases is associated with changes in lifestyle, including smoking, consumption of alcoholic beverages, physical...

Background: Vasera is a machine developed to evaluate arterial stiffness by measuring pulse wave velocity (PWV) and cardio-ankle vascular index (CAVI), apparently independent of blood pressure (BP). The 4-cuff device measures right (R) and left (L) brachial and ankle BP, deriving the CAVI value and cardiac-ankle...

Objective: To study the determinants of Arterial Stiffness (AS) in the elderly. Design and method: Cross-sectional, observational study of elderly participants. Blood Pressure (BP) and arterial function parameters were measured with a validated device. Clinical and demographic information was gathered,...

Objectives: A number of non-invasive devices have been used to measure arterial stiffness in COPD. The aim of this study was to compare the Complior device with the gold standard SphygmoCor Vx device, in patients with COPD and healthy volunteers. Methods: Aortic PWV was measured during a single visit...

Background: Pulse Wave Velocity (PWV) is a measure of arterial stiffness and vascular aging and an important parameter for cardiovascular risk stratification. A previous study showed high prevalence rates of early vascular aging in an adult population from the North of Portugal. The aim of this study...

The purpose of the research was to assess the functional state of the cardiovascular system of men in Yakutia of 22–60 years old (depending on the age group). A morphofunctional survey included 295 men of the first mature age (21–35 years old) and 502 men of the second mature age (36–60 years old). An...

Anemia is a condition in which the number of red blood cells, or hemoglobin concentration is below. The prevalence of anemia is mostly due to iron deficiency. About 50% of anemia in women worldwide is caused by iron deficiency (WHO, 2012). This study aims to determine the correlation of menstrual patterns...

Purpose/Background/Objective: Peripheral arterial disease (PAD) is a common manifestation of atherosclerosis and obesity is one of its well-established risk factors 1–5. PAD is classified in intermittent claudication (IC) and critical limb ischemia (CLI), according to the its severity6. Therefore, we...

Aim: To evaluate the relation between arterial stiffness and left ventricular diastolic dysfunction (LVDD) in metabolic syndrome (MetS) patients during more than 3 years observation period (average was 3,8 years). Methods: This longitudinal study enrolled 573 subjects (aged 53,4 ± 6 years, 63% female,...

Background: The relation between telomere dynamics and obesity remains unclear. Cross-sectional studies found associations between short leukocyte telomere length (LTL) and high body mass index (BMI) but longitudinal studies did not find any association between LTL attrition and BMI. In two parallel...

Objectives: The popliteal artery resemble the carotid artery in structure and function1. The aim of this study was to determine whether the popliteal artery resemble the carotid artery in structure and function in young and older Caucasian men and women. Methods: Hundred and twenty Caucasian men and...

Background: Ultrahigh-frequency ultrasound may represent a powerful tool for investigating the arterial properties of medium and small-size arteries. Aim of this study was: 1) to evaluate intra- and inter-operator reproducibility of radial artery vascular parameters (intima-media thickness –IMT- and...

Caries are a major dental health problem in Indonesia, especially in school-aged children, that affect the children’s dietary habits and growth. Taste perception is one of the determining factors of children choosing certain types of food that affect oral health and BMI. The research aimed to investigate...

It has been suggested that measurement of “unattended” blood pressure values may provide advantages over conventional BP measurement; some hypertension guidelines now suggest this approach as the preferred one for measuring office BP. Data on the relationship between unattended BP and cardiovascular...

Objectives: up to date the assessment of coronary artery disease (CAD) risk is based mainly on the presence of CV risk factors. However, many markers of subclinical atherosclerosis has been demonstrated as powerful predictors of CV events. Aim of our study was to evaluate if non invasive US parameters,...

Objective: Our aim was to examine the impact of mismatch patterns reflecting pre- and post-natal growth conditions on markers of arterial stiffness and central hemodynamics in young adults. Methods: In all, 1056 participants from Malmö Offspring Study, 484 men and 572 women (age-range 18–44 years),...

Background and Aim: Low density lipoprotein cholesterol (LDL-C) is a primary risk factor for atherosclerosis, but it is also associated with elevated blood pressure (BP) and future development of hypertension. We examined the relationship between LDL-C and haemodynamic variables in normotensive and never-treated...

Background: Exercise is part of antihypertensive therapy. However, little is known about the effect of different types of exercise on hemodynamic variables in systemic arterial hypertension (SAH). Purpose: To evaluate the effect of an aerobic (AE), resistance (RE) and combined (CE) exercise session on...

Objectives: Left ventricular (LV) concentric remodeling predicts all cause and CV mortality in various subsets of patients. Large arteries stiffness determines cardiac afterload and therefore LV remodeling. Since elastic properties of the arterial wall vary along the aortic pathway, we hypothesized that...

Type 2 diabetes (DM2) and poor glycemic control adversely affect common carotid intima media thickness (IMT), considered marker of preclinical atherosclerosis. However, studies evaluating the effect of DM2 and glucose levels on IMT did not consider carotid diameter, known to affect IMT. A certain IMT...

Background Laryngopharyngeal reflux (LPR) is a disease caused by the backflow of stomach contents into the laryngopharynx. In 2018, 20-30% of patients with laryngeal complaints were diagnosed with LPR in Indonesia. Aims: To determine the prevalence of LPR cases at Dr. Hasan Sadikin General...

Background: Individuals with Down Syndrome (DS) have autonomic dysfunction impacting regulation of heart rate, Blood Pressure (BP), and peripheral vasoconstriction. This may alter central hemodynamics through different wave reflections. We investigated central hemodynamics including wave reflection during...

Objective: The ASINPHAR@2action programme aims at raising awareness to early vascular ageing (EVA) through a community-based intervention. This preliminary analysis is focused on the analysis of the proportion of participants with abnormal arterial stiffness (AS) and the definition of its main determinants. Design...

Background: Markers of central haemodynamics have in recent years emerged as promising predictors of cardiovascular disease (CVD). Central haemodynamics are affected early in the development of vascular aging and affect organs directly attached to large arteries. Carotid-Femoral pulse wave velocity (c-f...

Background: Cardiovascular disease is a leading cause of disease progression and death in multiple sclerosis (MS). Obesity has a negative impact on vascular structure and function, but whether this contributes to worse vascular function similarly in individuals with MS and controls is unknown. Aim:...

Objective: Systemic lupus erythematosus (SLE) is a chronic inflammatory disease associated with vascular derangement [1]. Leptin and adiponectin are adipokines with immunomodulatory and vascular functions [2]. We studied the association between arterial stiffness and plasma leptin and adiponectin levels...

Introduction: Increased arterial stiffness (AS) in adults causes increased left ventricular (LV) afterload, putting additional strain on the heart. Long-term, this can lead to an adverse cardiovascular phenotype and AS has been found to be a determinant of CVD, independent of traditional cardiovascular...

The relationship between physiological and psychological well-beings among adolescents has always been studied extensively by researchers, yet few researches focuses on the impact of contextual factors such as school type, and demographic factors such as gender on the relationship between physical and...

Background/ Objective: Vascular growth factors angiopoietin-1 (Ang1) and -2 (Ang2) regulate vascular permeability and inflammation, Ang2 likely as Ang1’s selective antagonist. Their role before or in type 2 diabetes (pre-&T2D) is unknown. We hypothesised that higher circulating Ang1 and lower Ang2...

Background: Obesity is linked to a higher prevalence of risk factors, metabolic and inflammatory pathways conducting to increased vascular disease and CV risk. Objective: To assess vascular disarrangements and haemodynamic patterns in obese young subjects (O) compared with matched lean (L) controls,...

This research aims to establish the reference values of genitometric parameters in young men of the pubertant period living in the Republic of Sakha (Yakutia) and the peculiarities of their relation with somatometric and physiometric indicators. 74 young men of Yakut nationality were examined by standard...

Objective: Ambulatory Arterial Stiffness Index (AASI) and symmetric AASI (sAASI) have been proposed as indices of arterial stiffness obtained by 24-hour ambulatory blood pressure monitoring (ABPM). ABPM allows the analysis of indices of BP variability like day and night SD, BP dipping, weighted 24-h...

Background: Sedentary behavior has deleterious effects on cardiovascular risk. Uninterrupted sitting is associated with an impaired peripheral blood flow and vascular function. However, the relation between cerebrovascular flow and sedentary behavior is currently unknown. Impaired cerebrovascular flow...

Hypertension, even when pharmaceutically controlled, may accelerate arterial stiffening and impair changes in blood flow necessary to support neural activity (neurovascular coupling [NVC]). Optimal NVC requires continuous, non-pulsatile flow, which is partially determined by extra- and intra-cranial...

Prevalence of diabetes mellitus in the world has increased significantly in the last decades. Post meal physical exercise studies could improves blood glucose levels in diabetic patients. Plyometric exercise is a simple body movement that usually uses in body weight management. Therefore the aim of this...

Purpose/Background/Objective: Hypertension has been considered as one of the most common modifiable risk factors for stroke and cognitive impairment. Decreased cerebral perfusion and oxygenation, as a result of capillary rarefaction and microvascular impairment of brain vessels, have been suggested as...

Objective: To investigate the influence of weight excess and blood pressure (BP) on vascular structure and function in a sample of obese children. Methods: We measured office and ambulatory BP (ABPM), carotid intima-media thickness (cIMT), endothelial function by the Flow Mediated Dilation (FMD) technique,...

Objectives: Cardiovascular disease is a leading cause of death in multiple sclerosis (MS), and recent data showed that subclinical markers of atherosclerosis are higher in MS as well. Prevalence of MS in men is much lower than in women, but their prognosis is much worse. Men with MS also have higher...

Background: Systemic arterial hypertension (SAH) is one of the major risk factors related to the development of cardiovascular diseases (CVD). Sodium intake is linked to elevated blood pressure and can be estimated by 24-h urinary sodium excretion. The objective of this study was to correlate 24 h urinary...

Context: School adolescents in Porto Alegre have a mean physical inactivity (PI) <300 min/week of 43%, and another 13% do not perform physical activities. In this scenario, endothelial cells that regulate vascular homeostasis by the expression of bioactive mediators may be influenced by inflammatory...

Introduction: Individuals with multiple sclerosis (MS) exhibit impaired cerebrovascular function and have poor sleep quality. In the general population, poor sleep contributes to cerebrovascular dysfunction and is related to cardiovascular disease (CVD). Improving sleep quality may have beneficial effects...

Hypertriglyceridemia is a risk factor for metabolic syndrome and cardiovascular disease. Obesity often has a correlation with hypertriglyceridemia. Neck circumference (NC) is an anthropometric method of measuring upper body obesity. It is easy to use , innovative and time-saving. The aim of this study...

Inflammatory bowel disease (IBD) is characterized by a chronic recurrent inflammation of the gastrointestinal tract . The environmental factors affecting IBD include diet, the use of antibiotics and nonsteroidal anti-inflammatory drugs (NSAIDs) and stress. All of which can directly or indirectly affect...