Dr. Sulaiman Al Habib Medical Journal

Latest Articles

Research Article

Risk Factors associated with COVID-19 Infection among Contacts of Index Cases in Saudi Arabia: A Case-Control Study

Osama Kiram, Shumukh Alhejaili, Alwaleed Abdulhameed Alharbi, Ammar Alrudayan, Kurubaran Ganasegeran, Mohammad A. Alharbi, Mariam A. Alharbi, Sami Abdo Radman Al-Dubai
Volume 3, Issue 4, December 2021, Pages 188-193
This study was aimed to determine the risk factors associated with COVID-19 infection among contacts of index cases in Saudi Arabia. This unmatched case–control study was conducted among contacts of confirmed COVID-19 cases in April and May 2020 in Al-Madinah, Saudi Arabia. A total of 118 cases and 115...
Case Report

Congenital Candidiasis in a Preterm Neonate: Raising Awareness of a Rare and Unpredictable Disease

Rami Abuhajj, Mohamed Abdoun, Baneen Syeda, Rasha Abdulla, Abdulrahman Al Zahrani
Volume 3, Issue 4, December 2021, Pages 144-146
Congenital cutaneous candidiasis is a rare disease that is usually misdiagnosed as a type of benign neonatal eruption. We report on a preterm infant born with diffuse skin rashes that evolved into various forms and misleading the diagnosis. The persistence of respiratory distress and worsening of chest...
Research Article

Virtual Screening and Inhibition of Middle East Respiratory Syndrome Coronavirus Replication by Targeting Papain-like Protease

Mahmoud Kandeel, Byoung Kwon Park, Mohamed A. Morsy, Katharigatta N. Venugopala, Kentaro Oh-hashi, Mohammed Al-Nazawi, Hyung-Joo Kwon
Volume 3, Issue 4, December 2021, Pages 179-187
Infection by the emerging, potentially zoonotic Middle East Respiratory Syndrome Coronavirus (MERS-CoV) presents a severe health hazard to humans and is often fatal. Given the lack of particular medicines against MERS-CoV, drug discovery studies are needed to bridge this knowledge gap. In this study,...
Case Report

Hepatic Artery Aneurysm in Granulomatosis with Polyangiitis

Sora S. Boustany, Sammy Y. Tawk, Charbel J. Mourad, Beatrice A. Karam
Volume 3, Issue 4, December 2021, Pages 140-143
Large vessel involvement and arterial aneurysms are not typically encountered in Granulomatosis with Polyangiitis (GPA), which is a small vessel disease. We report the case of a 70-year-old male presenting with a ruptured hepatic artery aneurysm and elevated Antineutrophil Cytoplasmic Autoantibody, Cytoplasmic...
Research Article

In silico-based Discovery of New Potential Drugs Targeting Severe Acute Respiratory Syndrome Coronavirus 2 Spike Glycoprotein

Hayam Abdelkader, Mahmoud Rifaat, Mohammed Baghdadi, Nariman Sindi, Radwa Rifaat
Volume 3, Issue 4, December 2021, Pages 168-178
The SARS-CoV-2-induced novel coronavirus disease has become a global pandemic. As the latest coronavirus variants are even more infectious and deadly, its treatment is very difficult. Currently used drugs such as remdesivir, saquinavir, and chloroquine have several drawbacks. Recent studies have reported...
Research Article

Prevalence and Factors Associated with under-5 Mortality in Nigeria: Evidence from 2018 Nigeria Demographic and Health Survey

Ashis Talukder, Nusrat Jahan Sathi, Md. Akhtarul Islam, Sheikh Mohammed Shariful Islam, Iqramul Haq
Volume 3, Issue 4, December 2021, Pages 154-161
Under-five mortality is a substantial indicator of children’s health, well-being, and consequently, socioeconomic development of a country. The primary focus of this study was to estimate the prevalence and identify the factors associated with under-5 mortality in Nigeria. This research utilized the...
Review Article

Glucocorticoids Use and Post-Hospitalization Outcomes among Patients with Coronavirus Disease 2019: A Systematic Review of Observational Studies with Meta-Analysis

Ebtihag O. Alenzi, Hanaa O. Alenizi
Volume 3, Issue 4, December 2021, Pages 133-139
Background: A systematic review with meta-analysis was conducted to assess the association of glucocorticoids use with the likelihood of all-cause mortality in cases with Coronavirus Disease 2019 (COVID-19). Methods: Databases and cross-referencing were searched for observational studies about patients...
Research Article

COVID-19 Vaccine Knowledge, Attitude, and Acceptance among Students in Selected Universities in Nigeria

Adebowale Jeremy Adetayo, Basheer Abiodun Sanni, Mariam Oyinda Aborisade
Volume 3, Issue 4, December 2021, Pages 162-167
This study sought to examine the relationship between knowledge, attitude, and acceptance of Coronavirus Disease 2019 (COVID-19) vaccine among students in selected universities in Nigeria. An anonymous survey was conducted online among Nigeria students. The questionnaire collected demographic characteristics,...
Research Article

Lung Ultrasound using a Handheld Device to Diagnose COVID-19 in the Emergency Department

Abdulrahman M. Alfuraih, Abdussalam A. Alshehri, Hani M. Alshehri, Sami A. Alamri, Tariq S. Aleyyed, Khalid G. Alaufi, Mohammed J. Alsaadi
Volume 3, Issue 4, December 2021, Pages 147-153
The Coronavirus Disease 2019 (COVID-19) pandemic has critically struck healthcare systems and burdened emergency services. To date, there is no accurate and rapid point-of-care diagnostic test. This study aimed to investigate Lung Ultrasound (LUS) against Reverse Transcription-Polymerase Chain Reaction...
Case Report

Paraplegia Due to Stent Fracture, after Thoracic Endovascular Aortic Repair for Blunt Thoracic Aortic Injury: A Case Report and Review of Literature

Hussein Ahmed Lateef, Ahmed Sameer Mahmud Nadeem, Mutaz I.K. Fakhry Al-Khateeb, Adel Aswad
Volume 3, Issue 3, September 2021, Pages 93-98
Thoracic Endovascular Aortic Repair (TEVAR) became the standard treatment for patients with Blunt Thoracic Aortic Injury (BTAI) because it is a minimally invasive intervention, with proven lower morbidity and mortality compared with open surgery, especially in multiple trauma patients. However, there...
Research Article

Drug Repurposing of Lactoferrin Combination in a Nanodrug Delivery System to Combat Severe Acute Respiratory Syndrome Coronavirus-2 Infection

Assem Barakat, Abdullah Mohammed Al-Majid, Gehad Lotfy, Mohamed Ali, Ahmed Mostafa, Yaseen A.M.M. Elshaier
Volume 3, Issue 3, September 2021, Pages 104-112
A drug repurposing approach for Food and Drug Administration (FDA)-approved drugs and preclinical entity by using cheminformatics and chemical transformational method, with the objective of discovering safer novel potent inhibitors that are selective for COVID-19, is reported. We examined the action...
Research Article

Hospital-acquired Respiratory-Tract Infections in the Teaching Hospitals of Sfax

Maissa Ben Jmaa, Sourour Yaich, Houda Ben Ayed, Maroua Trigui, Mariem Ben Hmida, Habib Feki, Jamel Damak
Volume 3, Issue 3, September 2021, Pages 113-119
Hospital-acquired Respiratory-Tract Infections (HARTIs) are identified as the most frequent type of hospital-acquired infections. They can engender significant morbidity and mortality rates, generating a heavy economic burden, especially in the limited resources countries. In this perspective, this study...
Case Report

Neonatal Hemochromatosis: Treatment with Exchange Transfusion and Intravenous Immunoglobulin

Ehab Mohamed Hantash, Abdulrahman Al Zahrani, Mohamed Abdoun, Syeda Naqvi, Georges E. Nawfal
Volume 3, Issue 3, September 2021, Pages 99-103
Neonatal Hemochromatosis (NH) is a rare phenotype of severe fetal/neonatal liver injury that is accompanied by extrahepatic siderosis. Current clinical evidence shows that NH is not a disease per se, but is the consequence of fetal liver injury. Gestational alloimmune liver disease is the cause of nearly...
Short Communication

Forecasting COVID-19 Cases in Algeria using Logistic Growth and Polynomial Regression Models

Mohamed Lounis, Malavika Babu
Volume 3, Issue 3, September 2021, Pages 83-87
Coronavirus disease 2019 (COVID-19) continues to spread worldwide since its emergence in December 2019 in Wuhan, China, and as of January 3, 2021 more than 84.4 million cases and 1.8 million deaths have been reported. To predict COVID-19 cases in Algeria, we applied two models—the logistic growth model...
Research Article

Adherence to Stress Ulcer Prophylaxis Guideline in Medicine Unit at Soba University Hospital: A Descriptive Retrospective Study

Alaa A. Elmubarak, Safaa Badi, Bashir A. Yousef
Volume 3, Issue 3, September 2021, Pages 125-130
Although several guidelines for Stress Ulcer Prophylaxis (SUP) have been published, Acid-Suppressive Therapy (AST) remains largely prescribed in hospitalized patients. Thus, our study aimed to evaluate the current practice surrounding SUP in Soba University Hospital (Khartoum, Sudan). This descriptive...
Research Article

Diagnostic Accuracy of Multiple Detector Computed Tomography in Detecting Mandibular Invasion in Oral Squamous Cell Carcinoma

Anum Saher, Adeel Ahmed Khan, Muhammad Saad Ahmed, Syed Mubarak Ali
Volume 3, Issue 3, September 2021, Pages 120-124
The prediction of bony involvement of the mandible in oral Squamous Cell Carcinoma (SCC) by taking imaging scans prior to surgery is an important issue. The objective of our study was to determine the diagnostic accuracy of Multiple Detector Computed Tomography (MDCT) in detecting mandibular involvement...

Estimating the Incidence of SARS-CoV-2 Cases in Belize Based on Mortality Rate

Paul Morgan, Cyleen Morgan, Chieh-Wen Ed Hsu, Biru Yang
Volume 3, Issue 3, September 2021, Pages 88-92
Developing countries such as Belize have been facing profound challenges in their quest to effectively track cases of Coronavirus Disease 2019 (COVID-19) and contain the pandemic within their own territory. We assume that at the heights of a COVID-19 wave the number of daily reported cases are substantially...
Review Article

Molecular Testing for COVID-19: What the Clinician Should Know

Nermin Kamal Saeed, Mohammed Al-Biltagi, Adel Salah Bediwy
Volume 3, Issue 2, June 2021, Pages 53-59
Coronavirus Disease 2019 (COVID-19) is a major challenge for health systems worldwide. Molecular diagnosis is a cornerstone in the management of COVID-19. Clinicians should understand the various aspects of molecular testing that may influence their judgment and management. Cycle threshold, viral shedding,...
Research Article

Covid-19 Vaccinated and Positive Rate of Infection in Israel and the United Arab Emirates

Alberto Boretti, Sarim Al Zubaidy
Volume 3, Issue 2, June 2021, Pages 78-82
Thanks to the high vaccination rates posted in Israel and the United Arab Emirates since mid-December 2020, by end of March 2021 a significant portion of the population has been vaccinated. This adds to the percentage of those who have been infected and have recovered, protected to a different extent...
Review Article

Treatment Options during Cytokine Storm

Abdullah Alkattan, Kentaro Oh-hashi, Mahmoud Kandeel
Volume 3, Issue 2, June 2021, Pages 48-52
Cytokine storm is the major cause of death in patients with acute respiratory distress caused by COVID-19. Because cytokine storm is a life-threatening condition, it is important to treat patients with the most appropriate drugs depending on their infectious pathogen and medical status. In this short...
Research Article

Seroprevalence of Hepatitis B Virus in HIV Tested Positive Patients Accessing Treatment in Specialist Hospital Jimeta

Mohammed Bashir, Halima Ibrahim, Halima Isa
Volume 3, Issue 2, June 2021, Pages 74-77
Background: Human Immunodeficiency Virus (HIV) positive patients are likely to be at risk of other infectious pathogens such as Hepatitis B Virus (HBV). HIV and HBV are blood-borne pathogens and are transmitted via intravenous drug use, sexual contact, or mother to child during pregnancy or birth. Objective:...
Review Article

Is a History of Type 1 Allergic Diseases Associated with the Risk of Developing Multiple Sclerosis?

Abdulrahman Alfawzan, Saeed Alshahrani, Ahmad Alswaidan, Ala Alkharaan, Hayyaf Aldossary, Awad Almuklass
Volume 3, Issue 2, June 2021, Pages 60-65
Multiple Sclerosis (MS) is an autoimmune disorder affecting the central nervous system, characterized by demyelination of the neurons with limited remyelination. There has been a rising trend toward associating a history of allergy with MS. Both MS and type 1 allergies are developed by a hyper-reactive...
Case Report

Unusual Presentation of Congenital Ileal Stenosis in a Neonate

Ehab M. Hantash, Syeda Naqvi, M. Abdoun, Ibrahim Sbou, Abdulrahman Al Zahrani
Volume 3, Issue 2, June 2021, Pages 45-47
The presentation of congenital intestinal stenosis in neonates can vary from mild intermittent feeding intolerance resulting in difficulty of clinical judgment to profound obstruction. This report describes one case of ileal stenosis whose radiological investigations were not favoring intestinal obstruction...
Review Article

Comparing the Sub-Vastus and Medial Parapatellar Approaches in Total Knee Arthroplasty: A Meta-Analysis of Short-Term Outcomes

Mohamed Sukeik, Mohammad Zain Sohail, Fahad Siddique Hossain, Sattar AlShryda, James Powell
Volume 3, Issue 2, June 2021, Pages 66-73
Proponents of the Sub-Vastus (SV) approach in primary Total Knee Arthroplasty (TKA) claim superior extensor mechanism function which results in earlier recovery after surgery. We performed a meta-analysis of randomized controlled trials comparing the SV and standard Medial Parapatellar (MPP) approaches...