To study the biotherapy effect of Shenfuweikang herbs in treatment of gastric cancer, Kunming mice were grafted with a mouse gastric adenocarcinoma cell line MFC. Mice received different doses of Shefuweikang herbs after grafting. Tumor size was periodically measured and tumor weight was determined after...

3-Butyryloxy-16-(β-naphthylmethylene)-5α-androstane-17-one, a novel androstanone derivative, was synthesized by aldol condensation between epiandrosterone and β-naphthaldehyde and subsequent esterification reaction. The structure of the new product was characterized by 1H NMR, 13C NMR, IR, UV and mass...

Liquid culture of seleniferous mycelia of Pleurotus geesteranus Singer (SeMyc-P) was evaluated for its acute toxicity in supplement application and antioxidant against D-galactose induced oxidation damaged mice. Maximum Tolerant Dose (MTD) of SeMyc-P was about 20g/kg bw for mice to define safety application...

An efficient one-pot protocol for the synthesis of symmetrical diinosine triphosphate (Ip3I) and diinosine tetraphosphate (Ip4I) from inosine 5 -phosphoropiperidate has been developed. The experimental results indicated that the employment of DCI activation could notably promote the reaction rate and...

Objective: To investigate the levels of microRNA-21 (miR-21) in the serum of patients with spinal cord injury (SCI) and to determine whether there was a correlation with degree of injury. Methods: Quantitative real-time reverse transcription–polymerase chain reaction( q-RT-PCR)was used to measure the...

Spinal cord ischemia-reperfusion injury (SCII), which was proposed by Allen in 1911, is the secondary damage of primary spinal cord injury and the main reason resulting in nerve injury complication and sequela [1]. Ginsenoside is one of the ingredients of Ginseng and the monomer composition being purified...

Because of its simple experiment design and low experiment cost, label-free quantitative technology based on mass spectrometry analysis is being used more and more widely. Aiming at peptide identification and quantification, which are pivotal step of the label-free quantitative analysis, we develop an...

The present study was designed to evaluate the anti-fatigue effects of genistein in mice subjected to the forced swimming test. Mice were divided into four groups, i.e., one control group and three genistein treated groups. The treated groups were received doses of genistein (7, 15 and 30 mg/kg) dissolved...

According to estimates by oncologists, if early tumor diagnosis and treatment in a timely manner can be achieved in the millimeter level or below, the cure rate of cancer will be able to increase to 80%-90%. With the rapid development and maturity of nano technology and scientific theory, Up-conversion...

Objective: To investigate the effect of androgen on female individuals. Methods: In the physiological, pathological and pharmacological conditions, we summarize the role of androgen in female individuals, analyze its current research situation, and speculate the possible research direction. Results:...

Objective: To investigate the molecular mechanism of benign prostatic hyperplasia (BPH) and the characteristics of traditional Chinese medicine in the treatment of BPH. Method: Around bFGF/ERK, TGF-β/Smad pathway and related apoptosis gene expression, By analyzing the expression of TGF-β, bFGF and their...

The 5-year survival is only about 30% when ovarian cancer (OC) is first detected at an advanced stage, which is the case for ~70% of women with OC. The combination of debulking surgery and cytotoxic chemotherapy is the primary treatment modality for OC. There has been much interest in the use of intraperitoneal...

The experiment was conducted to compare the effect of nano-selenium and sodium selenite on blood biochemistry, liver antioxidant activity and GPx-1 mRNA expression in rabbit. Twenty-four 10-week-old New Zealand rabbits, female and male in half, were randomly divided into three groups. Rabbits in Group...

Magnetic hyperthermia is a non-invasive cancer treatment used synergistically with the existing cancer treatments. The challenges of an efficient magnetic hyperthermia are improved biocompatibility and enhanced heating characteristics. We have addressed both the challenges by fabricating globulin conjugated...