Search all articles

Phytochemical tests of coffee show that coffee contains antioxidant compounds, which play a role in the healing process of disease. However, it is necessary to know the safe dosage of coffee extract used in treating diseases including its effect on important organs such as the liver and kidneys. The...

This paper investigates how Malaysia and India incorporate the Sustainable Development Goals (SDGs) into their operations. The alignment of sustainable corporate practices was identified and measured. The authors employed a qualitative research design to analyze data collected from numerous industries....

Through 4 weeks HiLo training of 72 SD male rats, some very obvious changes of Rat skeletal muscle SDH was found in a quiet state. Some changes of SDH were found immediately after exercise but not obvious, but three hours later after exercise the change of Hypoxia and exercise compound group was more...

The black swan event has the characteristics of rarity and serious consequences. At present, the analysis of black swan events is generally preconceived (that is, the event is assumed to be a black swan event, and then the influence of the event is discussed), or whether it is a black swan event is directly...

Our previous study in young spontaneously hypertensive rats (SHR) confirmed a participation of nitric oxide (NO) and hydrogen sulphide (H2S) in probably inherent adaptive strategy of conduit arteries in condition of sustained hypertension. The aim of study was to confirm or refuse the compensatory mechanisms...

The effects of the selective angiotensin AT2 receptor agonist, compound 21 (C21), on abdominal aortic aneurysm (AAA) formation were investigated in normotensive Wistar rats. AAA was induced by perfusion of isolated aortic segments with elastase (Anidjar/Dobrin model). Treatment with C21 (0.03 and 0.3...

Objectives: Several studies have observed that altered endothelial function is involved in the development of stress-induced hypertension. The aim of this study was to investigate the effects of chronic social stress (crowding) on endothelium-dependent relaxation (EDR) of the superior mesenteric artery...

Background: Hypertensive humans exhibit reduced nitric oxide bioavailability and increased salt sensitivity, both of which are related to central artery stiffening. We studied the effect of 5 week NO restriction via L-NAME treatment in spontaneously hypertensive rats (SHR) and 5% salted diet in salt-sensitive...

This study investigated the effects of feeding rats for 24 months on different unsaturated fats (virgin olive, sunflower, or fish oil) on gingival mitochondrial ultrastructure and expression of genes related to mitochondrial biology as well as the amount of circulating fatty acids in the plasma. Results...

IVI Configuration Store is the key factor in the interaction between users and instruments. Usually, users need a GUI configuration utility to write the configuration information into IVI Configuration Store. But the IVI Foundation does not offer a specific configuration utility. In this paper, a configuration...

Traditionally applied medicinal plants are of great importance, and the trend of using these medicinal plants is increasingly important in the world due to their fewer side effects. Madhumeha Nivarana Churnam is an indigenous ayurvedic formulation is focused on this research study to establish the claimed...

Introduction: Arterial restenosis after angioplasty/stenting has hindered coronary artery disease treatment, especially in diabetics. We theorized that gastrin-releasing peptide (GRP) antagonists and growth hormone-releasing hormone (GHRH) antagonists might decrease neointimal hyperplasia and restenosis...

Diabetes Mellitus (DM) refers to a group of metabolic disorders marked by elevated blood glucose levels, which occur as a result of abnormalities in insulin production, its effectiveness, or a combination of both. Combination therapy for DM patients includes dietary intake and increased physical activity....

Mesenchymal stem cells (MSCs) can differentiate into neurons, which can be used in cell therapy. Endogenous genes and neurotrophic factors such as nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin-3 regulate neural stem cell proliferation and differentiation (NT-3)....

Prolong teeth loss due to dental extraction causes interference with the Temporomandibular Joint (TMJ), speech impairment and psychological aspects of aesthetics. For the fulfillment of general, dental and oral health, denture is needed to maintain necessary function of chewing. Generally, after tooth...

Pulmonary artery hypertension (PAH) is a progressive chronic disease with a high mortality rate. Increased pulmonary vascular resistance and over-proliferation of pulmonary artery endothelial cells lead to remodeling of pulmonary vasculature. Several anti-PAH therapies targeting various pathways involved...

The research was carried out at CV. ABC, a furniture manufacturing company that produces various types of furniture such as window frames, bed frames, chairs, and others. The common problem found in the company is the inability to meet production targets within the predetermined time frame. These problems...

Intermittent hypobaric hypoxia (IHH) is believed to have neuroprotective effect. IHH induces changes in gene expression and intracellular signaling pathways that lead to the emergence of intracellular adaptation through HIF-1 alpha gene activity. IHH induction decreased brain cortical tissue damage,...

Chronic liver disease commonly result in liver fibrosis and eventually liver cirrhosis. It has been demonstrated that patients with liver cirrhosis whom consumed N. sativa seed'sexperienced an improvement such as increasing of serum albumin level followed by diminished lower extremities oedem and ascites....

. Epilepsy (Epilepsy, EP) is a brain functional disorder caused by brain neurons abnormal discharge, however, the etiology and pathogenesis of epilepsy is still unclear. With the development of computer technology and digital signal processing technology, research and analysis of EEG signals is gradually...

Dental treatment is often associated with pain, fear, and anxiety. Unfortunately, children with dental anxiety tend to resist dental treatment and behave uncooper-atively during dental procedures. Dental treatment is known to be stressful and is often associated with a physiological response; therefore,...

Purpose: Loose endothelial cells and the destruction of the blood–brain barrier (BBB) are one of the pathophysiological mechanisms of early brain injury (EBI) after subarachnoid hemorrhage (SAH). Tie-2 receptor phosphorylation is important for maintaining integrity of microvascular endothelial cells...

Routing problem is one of the most important issues to a wireless sensor network (WSN). It is the key problem to find an efficient energy strategy for prolonging network's lifetime because power supply might be impossible. This paper discusses the multicast routing problem of WSN with multiple QoS constraints,...

Objective: Intestinal anastomosis is among the most commonly performed major abdominal procedures; however, leaks are an ongoing problem. The aim of this study was to investigate the effect of Insulin-like Growth Factor (IGF-1) on colonic healing under hypoxia. Methods: Thirty-two Sprague–Dawley male...

Paracetamol (acetaminophen) is a ubiquitous drug usually prescribed for its analgesic and antipyretic effects. It is a readily available over-the-counter medication. Consumption of jamu and paracetamol causes pharmacokinetic interaction. This study aimed to determine how much the potential of jamu “pegal...

Bone is a special composite material with excellent performance. This paper carries out numerical simulation of bone growth of femur in Wistar rat based on bone adaptive remodeling theory, integrated into the physiological regulation of bone growth. Proximal femur was scanned by Computed Tomography(CT)...

This paper presents the estimation of pu-rity of honey using Artificial Neural Network (ANN). ANN method was used to automate the decision of estimation, replacing the manual human approximate method. A total of 21 honey purity sam-ples from various concentrations of pure honey, adulterated honey and...

Silicosis, characterized by many cytokines expression, especially TNF-alpha and TGF-beta1, is the most prevalent occupational disease world-wide. Here we examined whether quercetin can regulate expressions of TGF-beta1 and TNF-alpha in lung of rats with silicosis. Totally 75 male Wistar rats, were randomly...

Background: Nigella Sativa (NS) induced vasorelaxation of aortic rings upon direct exposure has been documented in literature. This study was conducted to determine whether 8 weeks Nigella Sativa supplementation and/or exercise training may alter vascular sensitivity of rat aorta in normal, healthy rats. Methods:...

Background: Cardiac Arrest (CA) is one of the leading causes of mortality worldwide. The present study aimed to establish a simple and stable rat model of CA induced by transesophageal cardiac pacing for the investigation of cerebral resuscitation. Materials and Methods: A total of 26 healthy adult...

Growing evidence shows that patients with rheumatoid arthritis (RA) have up to twice the risk of developing cardiovascular disease (CVD) compared to those without RA. Generally, these RA patients have higher levels of inflammation in their bodies, and this inflammation is thought to be the link between...

Health services performed by health care professionals in the com-munity have an important meaning. Especially for remote indigenous communities (KAT) who live with all the difficulties, limitations, as well as limited on human resources, economics, geographical, social, and cultural conditions which...

The optimal management of hemodynamic disorders among critically ill patients requires an accurate assessment of hemodynamic status. Global End Diastolic Index (GEDI) is taken for a more reliable indicator of preload in critically ill patients than central venous pressure and doctors tend to arrange...

Preparation and percutaneous absorption of 2-methyl-2-perfluoro-2'-methyl-3'-oxoca- proyloxyl ethoxycarbonyl ethylmethyldipolyethoxylsilicane (V) were investigated. V was synthesized from 2-perfluoro-2'-methyl-3'-oxocaproyloxylethyl methacrylate and methyldichlorosilicane by hydrosilication, then by...

The ore transportation system of strip mines is a representative discrete-event sys-tem, so the data concerning facilities and resource are collected and extracted to obtain their statistical probability by Expertfit; Based on Flexsim, Then 3D model is developed, incarnating the relationship among transport,...

With the deepening of reform and opening-up, China’s domestic economy has evolved into an extraordinarily complex and diverse landscape, where social issues stemming from rat-race competition have become particularly pronounced. This paper utilizes questionnaire data from Chinese A-share listed companies...

Purpose: The retinal vasculature provides unique in vivo access to the microcirculation and presents the possibility of measuring small artery (retinal) stiffness using pulse wave velocity (PWV). This study investigates whether retinal artery PWV (rPWV) has a blood pressure (BP) dependency. Methods:...

Remanufacturing technology is an emerging technology, which is widely used in industrial field, since it prevents the recast of waste and outdated components through remanufacturing them again and guarantees that the quality of remanufacted components is not lower or even higher than new products. By...

Objective: This study aims to compare the cytotoxicity and adhesion difference between oxalate monohydrate (COM) and dehydrate (COD) crystals and African green monkey kidney epithelial cells (Vero). Methods: Through the detection of cell viability, lactate dehydrogenase (LDH) release amount, expression...

Porphyrin and its derivatives are widely investigated for cancer therapy because of their high selectivity to cancer cells. By labeling gamma and beta emitting-radionuclides to a porphyrin which selectively binds to the cancer tissue will produce a safe and potential radiopharmaceutical. The present...

Background: Interleukin-6 (IL-6) was considered to be with the severity and mortality in COVID-19 patients, which implies a potential therapeutic target for treatment. We aimed to evaluate the safety and initial efficacy of Tocilizumab treatment for COVID-19 patients. Methods: In the retrospective study,...

To study the effect of methamphetamine (METH) on embryonic development in rats. The number of male SD rats and female SD rats was 50 respectively, male and female rats were taken 30 respectively, which were used to establish the METH chronic poisoning rat model, after that, model animals were randomly...

Complete feed with high linoleic acid content may produce goat milk containing high linoleic acid too and it has specific protein with molecular weight of 42 kDa. The isolated milk peptide belong to goat milk containing 3.21% Linoleic acid (F2) and 4.80% (F3) can be promoted as candidate peptide with...

Holographic command and collaborate work are the breakthrough to traditional emergency management mode. Holographic command, as a kind of all weather, three dimensional and information-shared network interactive command platform, consists of sound, image, data and is featured with comprehensive, information-shared,...

Diabetes mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia that occurs due to defects in insulin secretion, insulin action, or both. Dyslipidemia is one of the risk factors for coronary heart disease and is often associated with diabetes mellitus. Statins are recommended by...

Setting up new strategies to prevent the growth and fatal rupture of aneurysms remains a challenge. The rat xenograft model of abdominal aortic aneurysm (AAA) has been used to develop gene and cell therapies with the aim of countering the expansion of the diseased arterial wall. It is of primary importance...

Background: In this study the effect of chronic ethanol consumption on vascular wall abnormality via oxidative stress was examined. It was also intended to find out whether vitamin E inhibits the abnormality induced by ethanol in rat vascular wall. Methods: Twenty-four male wistar rats were divided...

Introduction: Endovascular trophoblasts (EVasT) of the rat express smooth muscle (SM) proteins and contract ex vivo upon exposure to endothelin-1 (ET1). Contraction is mediated via ET1 receptors A and B (ETA, ETB). In vascular SM ETB, in variance from ETA, exerts relaxation through activation of nitric...

An important area of veterinary biotechnology is creation of medications made of plant tissues for prevention and treatment of various animal diseases. The objective was to study the new phytocomposition “Urticostim” effect on hematological and immunological blood parameters of rats. The experimental...

Purpose: Delirium is a frequent occurrence amongst Intensive Care Unit (ICU) patients, but studies on its causes are sparse and its risk factors vary from disease to disease. Here, in this study, an attempt was made to investigate the factors associated with the prognosis of delirium in the ICU. Methods:...